Peadar N Kirke Selected Research

Neural Tube Defects (Exencephaly)

4/2016	Evaluation of proton-coupled folate transporter (SLC46A1) polymorphisms as risk factors for neural tube defects and oral clefts.
10/2014	Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects.
2/2014	Is low iron status a risk factor for neural tube defects?
7/2011	Maternal folate, vitamin B12 and homocysteine levels in pregnancies affected by congenital malformations other than neural tube defects.
12/2009	A common variant in MTHFD1L is associated with neural tube defects and mRNA splicing efficiency.
7/2009	Lack of association between folate-receptor autoantibodies and neural-tube defects.
4/2009	The search for genetic polymorphisms in the homocysteine/folate pathway that contribute to the etiology of human neural tube defects.
4/2009	Analysis of the MTHFD1 promoter and risk of neural tube defects.
3/2009	Maternal vitamin B12 status and risk of neural tube defects in a population with high neural tube defect prevalence and no folic Acid fortification.
6/2008	Effects of folate and vitamin B12 deficiencies during pregnancy on fetal, infant, and child development.

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Peadar N Kirke Research Topics

Disease

19	Neural Tube Defects (Exencephaly) 04/2016 - 11/2002
3	Spinal Dysraphism (Spina Bifida) 02/2014 - 06/2007
2	Neoplasms (Cancer) 12/2009 - 10/2008
2	Congenital Abnormalities (Deformity) 06/2008 - 11/2002
2	Pregnancy Complications 07/2005 - 03/2002
1	Anencephaly (Aprosencephaly) 02/2014
1	Coronary Artery Disease (Coronary Atherosclerosis) 12/2009
1	Obesity 02/2009
1	Cleft Lip (Harelip) 09/2008
1	Cleft Palate (Palate, Cleft) 09/2008
1	Birth Weight (Birth Weights) 06/2008
1	Infections 06/2008
1	Anemia 06/2008
1	Megaloblastic Anemia 06/2008
1	Vitamin B 12 Deficiency (Vitamin B12 Deficiency) 06/2008
1	Spontaneous Abortion (Miscarriage) 07/2005
1	Abruptio Placentae (Placental Abruption) 02/2005
1	Down Syndrome (Down's Syndrome) 01/2002

Drug/Important Bio-Agent (IBA)

20	Folic Acid (Vitamin M)FDA LinkGeneric 04/2016 - 01/2002
6	HomocysteineIBA 07/2011 - 01/2002
6	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 07/2011 - 03/2002
5	EnzymesIBA 04/2009 - 01/2002
2	Formate-Tetrahydrofolate LigaseIBA 04/2009 - 11/2002
2	Methenyltetrahydrofolate CyclohydrolaseIBA 04/2009 - 11/2002
2	Methylenetetrahydrofolate Dehydrogenase (NADP) (Dehydrogenase, Methylenetetrahydrofolate)IBA 04/2009 - 11/2002
2	methionine synthase reductaseIBA 07/2005 - 01/2002
2	Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA 01/2003 - 01/2002
1	Proton-Coupled Folate TransporterIBA 04/2016
1	Choline (Choline Chloride)IBA 10/2014
1	IronIBA 02/2014
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 01/2011
1	Leptin ReceptorsIBA 01/2011
1	Brachyury protein (Brachyury)IBA 01/2011
1	Messenger RNA (mRNA)IBA 12/2009
1	AutoantibodiesIBA 07/2009
1	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2009
1	Uncoupling Protein 2IBA 02/2009
1	Proteins (Proteins, Gene)FDA Link 10/2008
1	VitaminsIBA 06/2008
1	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA 06/2007
1	Reduced Folate Carrier ProteinIBA 04/2006
1	Transcobalamins (Transcobalamin II)IBA 04/2005
1	Methylmalonyl-CoA MutaseIBA 12/2003
1	Folate Receptor 2IBA 06/2003